The strain library

The NAICONS microbial collection comprises 45k bacterial strains, mostly actinomycetes, isolated from >2,600 different sources. The strains were isolated using proprietary methods that favored slow-germinating strains or those producing motile spores. Most strains were isolated during the 1996-2006 period. The collection was acquired by NAICONS Srl in September 2013 and is fully ABS compliant.

As of September 2024, the 29%-portion of the collection that is 16S-classified includes over 100 genera belonging to 29 different families. The remaining 32k strains are classified on the basis of morphology into 18 distinct families.

There is full genome sequence information on 543 strains.

Taxonomic distribution of the 13k 16S-classified strains at family (inner circle; families with <50 strains are merged in a single group)

and genus (outer circle; only genera with >50 strains are shown) level. Numbers indicate the number of strains

  • The remaining 32k strains are classified, on the basis of morphology only, into 18 distinct families. The 16S-classified portion of the library is currently expanding. In addition, full genome sequences are available for about 500 strains.
Taxonomic distribution at family level of the 32k morphologically-classified strains. Families with <200 strains are merged in a single group. Numbers indicate number of strains.

The extract libraries

There are multiple copies of dried extracts in ready-to-screen 96-well microtiter plates (80 extracts per plate). As of September 2024, extracts include: i) 10,920 Full Extract (FE) prepared from processing an equivalent number of cultures from 9,733 different strains; ii) 65,520 partially fractionated extracts, prepared from the same cultures as in i); and iii) 7,440 extracts from 2,901 strains, prepared with a procedure that generated two extracts per culture

Distribution at family level of strains yielding the 10,920 FEs. Families with <200 strains are merged in a single group.

The extract library is being expanded by processing additional strains. 

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